Apoptosis and stem/progenitor cells in the development and treatment of cancer

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Project Title: Apoptosis and stem/progenitor cells in the development and treatment of cancer
Project Number: NHMRC-1113133
 
Project Description:
To improve cancer therapy, we are studying two cancer hallmarks. The first is excessive cell survival. To combat this, we are developing drugs with commercial partners that directly activate the cell's death machinery. The second hallmark is inexorable proliferation, akin to that of stem cells, which can generate entire tissues, as we showed for the breast. ‘Rogue’ stem-like cells may initiate certain cancers. We hope to advance cancer therapy by identifying such cells and drugs that kill them.
 
Project Terms:
apoptosis oncogenesis stem cells anticancer drug bcl-2
Project Title: Apoptosis and stem/progenitor cells in the development and treatment of cancer
Project Number: NHMRC-1113133
Organization: Walter And Eliza Hall Institute, Australia
Principal Investigators (PI): Strasser Andreas, AU
 
Project Categories:
Natural Sciences > Aging Diseases and Pathology > Cancer & related diseases > Malignant neoplasms (including in situ)
 
Other Information:
Fiscal Year: 2017
Project Start Date: 1 January 2016
Project End Date: 31 December 2021
Project program: Cancer Cell Biology
 
Project Funding Information:
Funding Mechanism: Program Grant
Year Funding Organization Total Funding, $
2015 National Health and Medical Research Council $15,921,012
Project Title: Apoptosis and stem/progenitor cells in the development and treatment of cancer
Project Number: NHMRC-1113133
 
Title FY Funding
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Project Title: Apoptosis and stem/progenitor cells in the development and treatment of cancer
Project Number: NHMRC-1113133
 
Project Title Organization FY Funding
Apoptosis And Stem/Progenitor Cells In The Development And Treatment Of CancerWalter And Eliza Hall Institute2015$15,921,012
Project Title: Apoptosis and stem/progenitor cells in the development and treatment of cancer
Project Number: NHMRC-1113133
 
Title Journal Year Country Rel
Project Title: Apoptosis and stem/progenitor cells in the development and treatment of cancer
Project Number: NHMRC-1113133
 
Title Year
Project Title: Apoptosis and stem/progenitor cells in the development and treatment of cancer
Project Number: NHMRC-1113133
 
Title Phase Year