European lead factory

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Project Title: European lead factory
Project Number: CORDIS-203710
Project web address: Follow on CORDIS
 
Project Description:
The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provide an industry-like small molecule discovery platform to public investigators. It builds on a unique, comprehensive, high-quality compound collection contributed by EFPIA Pparticipants, i.e. the Pharma Consortium Compound Collection totaling over about 300.000 compounds. Screening of these previously safeguarded corporate compound libraries against competitor’s targets and targets from public sources may result in otherwise inaccessible valuable lead structures that could ultimately result in the development of novel treatment options for patients. Academic Participantsa or other eligible bodies (and Contributing Third Parties) will be invited to submit proposals for screening of innovative targets and to suggest the design of new and diverse chemical libraries utilizing novel concepts and strategies. The latter will fuel the generation of a Public Compound Collection that will combine with the Pharma ConsortiumEFPIA Compound Collection to generate the Joint European Compound CollectionLibrary. These public sector contributions will not only provide a constant flow of innovation, but also generate opportunities for future partnerships amongst public Public Participants and private contributors EFPIA Participants on scientific and commercial grounds. EUC2LID’s overarching goal is value creation by screening the Joint European Compound Collection Library against in pPublic and private EFPIA Ttarget Programmes. Based on the successful delivery on its objectives during the IMI funding period, the generation of the high quality Public Compound Collection provides a tangible asset allowing the transition of the European Lead Factory into a novel sustainable business model, facilitating future public-private alliances based on pre-competitive, community-based efforts in early drug research.
 
Project Terms:
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Project Title: European lead factory
Project Number: CORDIS-203710
Project web address: Follow on CORDIS
Organization: Bayer Pharma Ag, Germany, Berlin
Collaborators: University Of Leeds, GB
University Of Nottingham, GB
University Of Dundee, GB
Stichting Katholieke Universiteit, NL
Danmark Tekniske Universitet, DK
The Chancellor, Masters And Scholars Of The University Of Oxford, GB
Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften Ev, DE
Academisch Ziekenhuis Leiden, NL
Janssen Pharmaceutica N.V., BE
Arttic, FR
H. Lundbeck A/S, DK
Merck Kommanditgesellschaft Auf Aktien, DE
Universitaet Duisburg-Essen, DE
Astra Zeneca Ab, SE
Universiteit Leiden, NL
Sanofi-Aventis Deutschland Gmbh, DE
Gabo:Mi Gesellschaft Für Ablauforganisation :Milliarium Mbh & Co. Kg, DE
Stichting Het Nederlands Kanker Instituut-Antoni Van Leeuwenhoek Ziekenhuis, NL
Ucb Biopharma Sprl, BE
Syncom, NL
Stichting Lygature, NL
Stichting Vu, NL
Lead Discovery Center Gmbh, DE
Taros Chemicals Gmbh & Co Kg, DE
Biocity Scotland Ltd, GB
Chemaxon Kutató-Fejlesztő Korlátolt Felelősségű Társaság, HU
Mercachem B.V., NL
Edelris S.A.S, FR
Sygnature Discovery Limited, GB
Bioascent Discovery Ltd, GB
Pivot Park Screening Centre Bv, NL
 
Project Categories:
Natural Sciences > Clinical Trials & Therapy > Treatment
 
Other Information:
Fiscal Year: 2013
Project Start Date: 1 January 2013
Project End Date: 31 December 2017
Project program: FP7-JTI
 
Project Funding Information:
Funding Mechanism: JTI-CP-IMI - Joint Technology Initiatives - Collaborative Project (IMI)
Year Funding Organization Total Funding, $
2013 European Research Council $213,630,871
Project Title: European lead factory
Project Number: CORDIS-203710
Project web address: Follow on CORDIS
 
Title FY Funding
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Project Title: European lead factory
Project Number: CORDIS-203710
Project web address: Follow on CORDIS
 
Project Title Organization FY Funding
Project Title: European lead factory
Project Number: CORDIS-203710
Project web address: Follow on CORDIS
 
Title Journal Year Country Rel
Project Title: European lead factory
Project Number: CORDIS-203710
Project web address: Follow on CORDIS
 
Title Year
Project Title: European lead factory
Project Number: CORDIS-203710
Project web address: Follow on CORDIS
 
Title Phase Year