Laboratory assay performance, coordination &oversight core

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Project Title: Laboratory assay performance, coordination &oversight core
Project Number: 5U54CA116847-05-9003
Project web address: Follow on NIH
Parent Project: 5U54CA116847-05
 
Project Description:
The Laboratory Core will provide personnel and supplies to process, store and analyze sera and plasma samples for projects 2-4. Conventional ELISA based assays will be performed including insulin, glucose, leptin, adiponectin, IGF-1, IGFBP3, plasma free fatty acids, CRP, SAA, and TNF-alpha. In addition, more novel assays including mass spectrometry based proteomic screens, apoptosis levels, DMA repair gene polymorphisms and expression levels will be performed. Most of these functions (i.e., specimen processing, many of the immunoassays, proteomics and gene expression/polymorphisms) will be performed on-site on the 5th floor of the new Public Health Sciences on the FHCRC campus. For some of the more specialized assays, we will collaborate with experts with demonstrated knowledge and proficiency with the particular assay. The Core Leader, Dr. Paul Lampe, will coordinate the assays both on-site and off-site, will receive and review regular assay reports for quality assurance and will coordinate with the administrative and statistical core to ensure that samples are properly handled, high quality assays are performed and data transfer to the statisticians is efficient.
 
Project Terms:
adiponectin apoptosis apoptotic base biological assay cancer prevention carcinogenesis collaborations data dna dna repair gene energy balance ensure enzyme-linked immunosorbent assay floor gene expression gene repair genetic polymorphism glucose health sciences human human resources human tnf protein igfbp3 gene immunoassay insulin insulin-like growth factor i knowledge laboratories leptin lymphocyte mass spectrum analysis molecular nonesterified fatty acids novel performance plasma process proteomics public health medicine (field) quality assurance rattus reporting sampling site specimen specimen handling t-cell receptor-rearrangement excision dna circles tumor necrosis factor-alpha prevention cancer genetics
Project Title: Laboratory assay performance, coordination &oversight core
Project Number: 5U54CA116847-05-9003
Project web address: Follow on NIH
Parent Project: 5U54CA116847-05
Organization: Fred Hutchinson Cancer Research Center, United States, Washington, SEATTLE
Principal Investigators (PI): Lampe Paul D, US
 
Project Categories:
Natural Sciences
 
Other Information:
Fiscal Year: 2009
Project Start Date: 1 September 2009
Project End Date: 31 August 2010
Project program: Specialized Center--Cooperative Agreements
 
Project Funding Information:
Funding Mechanism: Research Centers
Year Funding Organization Total Funding, $
2009 NIH - National Cancer Institute $241,720
Project Title: Laboratory assay performance, coordination &oversight core
Project Number: 5U54CA116847-05-9003
Project web address: Follow on NIH
Parent Project: 5U54CA116847-05
 
Title FY Funding
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Project Title: Laboratory assay performance, coordination &oversight core
Project Number: 5U54CA116847-05-9003
Project web address: Follow on NIH
Parent Project: 5U54CA116847-05
 
Project Title Organization FY Funding
Project Title: Laboratory assay performance, coordination &oversight core
Project Number: 5U54CA116847-05-9003
Project web address: Follow on NIH
Parent Project: 5U54CA116847-05
 
Title Journal Year Country Rel
Project Title: Laboratory assay performance, coordination &oversight core
Project Number: 5U54CA116847-05-9003
Project web address: Follow on NIH
Parent Project: 5U54CA116847-05
 
Title Year
Project Title: Laboratory assay performance, coordination &oversight core
Project Number: 5U54CA116847-05-9003
Project web address: Follow on NIH
Parent Project: 5U54CA116847-05
 
Title Phase Year