Recent news related to aging and gerontology

2018-03-11 | Brit scientists find way to SLOW ageing – and it’s SIMPLE

REVEALED: Scientists have found a way to stop ageing A huge study, published in Ageing Cell, has found cycling keeps you young past the age of 55. Scientists carried out tests on 125 amateur cyclists aged 55 to 79 and compared them with healthy adults who did not exercise regularly. ...

2018-03-08 | Cycling can hold back effects of ageing and may rejuvenate immune system

Cycling can hold back the effects of ageing and may rejuvenate the immune system, according to a new study. Scientists carried out tests on 125 amateur cyclists aged 55 to 79 and compared them with healthy adults from a wide age group who did not exercise regularly. ...

2018-03-07 | About 250 Genes That Cause Aging of the Brain Identified

A group of around 250 genes involved in age-related brain deterioration has been identified by scientists at the Babraham Institute, Cambridge and Sapienza University, Rome. The research finds that changes to one of these genes, called Dbx2, could prematurely age brain stem cells, causing them to grow more slowly. ...

2018-03-06 | Funding More Work on Deep Learning for Drug Discovery to Treat Aging

Recently Y Combinator announced their intent to fund companies working on treatments for aging. It is one of the many signs of a growing interest in this area of development in the venture community. ...

2018-02-28 | The global anti-aging market is expected to reach an estimated $66.2 billion by 2023 with a CAGR of 5.7% from 2018 to 2023 | Markets Insider

NEW YORK, Feb. 28, 2018 /PRNewswire/ -- The future of the anti-aging market looks good with opportunities in skin care and hair care. The global anti-aging market is expected to reach an estimated $66.2 billion by 2023 with a CAGR of 5.7% from 2018 to 2023. ...

2018-02-23 | Quantifying Nuclear DNA Mutation Rates in Stem Cells Doesn't Tell Us the Degree to which those Mutations Contribute to Aging

The study noted here provides numbers for the mutation rates in muscle stem cells, the stochastic damage that occurs over time as small numbers of errors slip past the highly efficient molecular machinery of cellular replication and DNA repair. The researchers used single cell genomic sequencing, a very useful and still comparatively new capability. ...

2018-02-21 | Crypto millionaires are funding research to reverse the aging process

Silicon Valley’s elite is famously fascinated by the promise of extreme lifespan extension—if not outright immortality. Research on these issues has drawn funding from the likes of Google, while the Bay Area’s Unity Biotechnology, which is developing drugs to treat diseases that accompany aging, has also raised a bunch of money. ...

2018-02-16 | Further Investigation of the Role of Osteopontin in Hematopoietic Stem Cell Aging

The Hematopoietic stem cell population resident in bone marrow is responsible for generating blood cells and immune cells. Like all stem cell populations, their activity alters and declines with aging. ...

2018-02-14 | Award supports research into how diet could take aim at aging cells - USC Leonard Davis School of Gerontology

With a new research award, USC Leonard Davis School of Gerontology Postdoctoral Researcher Sebastian Brandhorst will investigate how a “fast-mimicking” diet could target cells that show signs of aging for removal and potentially restore more youthful function. Aging is a major risk factor for the development of cancer, cardiovascular and neurodegenerative diseases. ...

2018-02-13 | Clues to aging found in stem cells' genomes

Stem cells that produce sperm use a genetic trick to stay perpetually young across generations, Howard Hughes Medical Institute (HHMI) Investigator Yukiko Yamashita and colleagues have discovered. Certain sections of the fruit fly genome get shorter with age. ...

2018-02-08 | Positive Beliefs About Aging May Reduce Risk Of Dementia—Even If You Have High-Risk Genetics

Thinking positively about aging might significantly reduce a person's risk of dementia, a new study has found—even for people with one of the strongest genetic risk factors. Researchers from Yale University and the National Institute on Aging studied nearly 5,000 people aged 60 and older, over a period of four years, and discovered those who held negative beliefs about aging were far more likely to develop dementia. ...

2018-02-06 | A More Subtle Demonstration that Telomere Length is Not a Good Measure of Aging

Researchers here find a disconnect between DNA methylation patterns shown to correlate well with age and processes associated with longer telomere length. Telomeres are caps of repeated DNA at the ends of chromosomes that shorten with each cell division, a part of the mechanism limiting the life span of somatic cells. ...

2018-02-06 | Could ageing immune systems be a better predictor of cancer than genetic mutations?

It has long been known that cancer arises when genes mutate and start producing abnormal proteins, or no protein at all. However, our latest research, published in PNAS, suggests that there is another, equally important mechanism by which cancer arises: an ageing immune system. ...

2018-01-28 | AstraZeneca plc isn’t the only way to play the world’s ageing population

There’s no denying the global population is getting older. Virtually every country in the world is experiencing growth in the number and proportion of elderly people within their populations. ...

2018-01-19 | The aging brain: A conversation with a cognitive psychologist | Scope Blog

My colleague Tracie White recently wrote about cognitive psychologist Ruth O’Hara’s research on worrying and its impact on cognition, memory and effective disorders in older adults. As White described: Worrying actually helps alleviate the negative effects on memory and cognitive processing caused by depression and anxiety in older adults, according to a new study published recently in Frontiers in Aging Neuroscience. ...

2018-01-19 | Silicon Valley Is Ready To Spend Millions More On Its Anti-Ageing Obsession

This month, the famed Silicon Valley startup accelerator Y Combinator put out a call for companies working to "help people live healthier for longer". If you're a scientist or entrepreneur who wants to increase human longevity and "healthspan", Y Combinator will give you up to $US1 million ($1.3 million) to do it. Y Combinator head Sam Altman. ...

2018-01-17 | Scientists reveal secrets of ‘anti-aging’ hormones | FierceBiotech

The hormones alpha-Klotho and beta-Klotho were named after one of three Greek “fates”: Clotho, a goddess who lays out the thread of life, the length of which is determined by her two sisters. They’re often called “anti-aging” hormones because of their reputed role in regulating metabolism and longevity. ...

2018-01-11 | Insilico Medicine develops new deep-learning based hematological human aging clock

January 11, 2018 Today, Insilico Medicine, Inc., a Baltimore-based company specializing in the application of artificial intelligence for drug discovery, biomarker development and aging research, announced a publication of a research paper titled "Population-specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern-European patient populations" in The Journal of Gerontology. In the paper, the authors present a novel deep-learning based hematological human aging clock, a biomarker that predicts the biological age of individual patients. ...

2018-01-08 | This Anti-Aging Serum Was Developed by Harvard Scientists—and I'm Obsessed With It

One of the many reasons why I love working in beauty? In addition to being fun and ever-evolving, the industry is backed by science. ...

2018-01-03 | Amanda Barrie, 82, reveals her anti-ageing secrets after wowing CBB fans with her incredible looks

AMANDA Barrie left Celebrity Big Brother fans completely gobsmacked last night as she made her incredibly glamorous entrance into the house. Taking to Twitter in their droves, viewers couldn’t quite believe the legendary actress is 82 and begged to know the secret behind her youthful appearance. ...

2018-01-02 | Anti-ageing research is nothing to fear | Cosmos

My father, at 96, liked to dress himself for the day but he was very slow. “The body betrays, Laurie,” he said to me. I responded by reading to my father a passage from Thomas More’s Utopia, which I had been studying as part of preparing a previous column for Cosmos. “Thus old men are honoured with a particular respect, yet all the rest fare as well as they. ...

2017-12-24 | Dreading the wrinkles? Here’s how you can protect your skin from ageing early

Skin ageing is a natural process. However, it gets accelerated due to fast-paced lifestyles, imbalanced diet and exposure to harsh weather conditions. ...

2017-12-20 | Restoring Aging Genes in Rats

Overexpression of a protein that regulates calcium homeostasis in hippocampal neurons can safely and effectively reverse and prevent age-related memory impairments in rats while restoring altered gene expression, finds new research published in JNeurosci. Philip Landfield, John Gant, Eric Blalock and colleagues found that long-term and short-term treatment of aging rats that induces overexpression of FK506-Binding Protein 12.6/1b (FKBP1b) restored the expression of more than 800 genes affected by aging to levels comparable to those of young untreated rats, in addition to improving performance on a water maze task. ...

2017-12-16 | Researchers track muscle stem cell dynamics in response to injury, aging

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) describes the biology behind why muscle stem cells respond differently to aging or injury. The findings, published in Cell Stem Cell, have important implications for therapeutic strategies to regenerate skeletal muscle in response to the normal wear and tear of aging, or in cases of injury or muscle diseases such as muscular dystrophy, medicalxpress.com wrote. ...

2017-12-14 | Working on a More Detailed View of Muscle Stem Cell Aging

The population of stem cells that supports muscle tissue is one of the better studied classes of such cell. Stem cells enable tissue maintenance and regeneration by delivering a supply of new daughter somatic cells that can multiple to make up losses, and through signaling that alters cell behavior. ...