European alternative splicing network of excellence

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Project Title: European alternative splicing network of excellence
Project Number: CORDIS-78768
Project web address: Follow on CORDIS
Organization: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften Ev, Germany, Dusseldorf
Collaborators: University Of Southampton, GB
Medical Research Council, GB
European Molecular Biology Laboratory, DE
University Of Edinburgh, GB
Tel Aviv University, IL
Uppsala University, SE
Hebrew University Of Jerusalem, IL
University Of Dundee, GB
University Of Leicester, GB
Medical University Of Vienna, AT
University Of Aarhus, DK
Consiglio Nazionale Delle Ricerche, IT
Centre National De La Recherche Scientifique, FR
The Chancellor, Masters And Scholars Of The University Of Cambridge, GB
Institut National De La Sante Et De La Recherche Medicale, FR
Universite De Geneve, CH
Universität Bern, CH
Fondazione Centro San Raffaele Del Monte Tabor, IT
International Centre For Genetic Engineering And Biotechnology, IT
Universitat Pompeu Fabra, ES
Eidgenoessische Technische Hochschule Zuerich, CH
Scottish Crop Research Institute, GB
Swiss Institute Of Bioinformatics, CH
International Institute Of Molecular And Cell Biology, PL
Centre De Regulació Genòmica, ES
Instituto De Medicina Molecular, PT
Centre Européen De Recherche En Biologie Et Médecine - Groupement D'Intérêt Economique, FR
Unversidad De Buenos Aires, AR
Principal Investigators (PI): Jean Beggs, GB
Peer Bork, DE
Maria Carmo-Fonseca, PT
Jorgen Kjems, DK
Janusz Bujnicki, PL
Frederic Allain, CH
Hermona Soreq, IL
Göran Akusjärvi, SE
Gil Ast, IL
Francisco Baralle, IT
Albrecht Bindereif, DE
Daniel Schümperli, CH
Ian Eperon, GB
Christopher Smith, GB
James Stevenin, FR
Juan Valcárcel, ES
Stefan Stamm, DE
Andrea Barta, AT
John W S Brown, GB
Javier Fernando Caceres, GB
Artur Jarmolowski, PL
Angela Krämer, CH
Angus Lain Lamond, GB
Giuseppe Biamonti, IT
Didier Auboeuf, FR
Davide Gabellini, IT
Mihaela Zavolan, CH
Alberto R Kornblihtt, AR
Jamal Tazi, FR
Eduardo Eyras, ES
Diana Baralle, GB
Reinhard Lührmann, DE
 
Project Description:
Posttranscriptional events must play a more central role in generating the highly complex proteomes of metazoa than previously believed. This is shown by the large discrepancy between the number of coding sequences of metazoan genomes and the known diversi ty of gene products that they generate. Indeed, alternative pathways for processing the primary transcript of a gene can theoretically generate more transcripts and, ultimately, more protein variants (i.e., isoforms) than the number of classically defined genes in an entire organism. Thus, the process of alternative splicing can greatly expand the information content of genomes. Alternative splicing is an essential component of gene regulation, affecting every aspect of eucaryotic biology, and understanding the mechanisms that lead to alternatively spliced transcripts is essential for the functional interpretation of genomic sequences. In addition, a large number of genetic diseases are caused by defects in the proper processing of primary transcripts, and a lterations in alternative splicing are the basis for multiple human pathologies including cancer, viral infection and inflammatory responses. Despite its prevalence and significance, the molecular mechanisms that regulate alternative splicing are poorly un derstood. The EURASNET consortium employs a wide range of complementary approaches as computational, biochemical, proteomic, genomic, cell and organismal biology to study post-transcriptional gene regulation and its role in disease. The primary purpose of this network will be to develop an integrated approach for the study of alternative splicing that will 1 ) provide durable structures that change the way research in this field is carried out in Europe, 2) establish an innovative and multidisciplinary prog ramme of joint research activities, 3)spread excellence within Europe by establishing a career platform for young investigators, and 4) disseminate knowledge to the wider research and medical
 
Project Terms:
biotechnology coordination and cooperation life sciences
Project Title: European alternative splicing network of excellence
Project Number: CORDIS-78768
Project web address: Follow on CORDIS
Organization: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften Ev, Germany, Dusseldorf
Collaborators: University Of Southampton, GB
Medical Research Council, GB
European Molecular Biology Laboratory, DE
University Of Edinburgh, GB
Tel Aviv University, IL
Uppsala University, SE
Hebrew University Of Jerusalem, IL
University Of Dundee, GB
University Of Leicester, GB
Medical University Of Vienna, AT
University Of Aarhus, DK
Consiglio Nazionale Delle Ricerche, IT
Centre National De La Recherche Scientifique, FR
The Chancellor, Masters And Scholars Of The University Of Cambridge, GB
Institut National De La Sante Et De La Recherche Medicale, FR
Universite De Geneve, CH
Universität Bern, CH
Fondazione Centro San Raffaele Del Monte Tabor, IT
International Centre For Genetic Engineering And Biotechnology, IT
Universitat Pompeu Fabra, ES
Eidgenoessische Technische Hochschule Zuerich, CH
Scottish Crop Research Institute, GB
Swiss Institute Of Bioinformatics, CH
International Institute Of Molecular And Cell Biology, PL
Centre De Regulació Genòmica, ES
Instituto De Medicina Molecular, PT
Centre Européen De Recherche En Biologie Et Médecine - Groupement D'Intérêt Economique, FR
Unversidad De Buenos Aires, AR
Principal Investigators (PI): Jean Beggs, GB
Peer Bork, DE
Maria Carmo-Fonseca, PT
Jorgen Kjems, DK
Janusz Bujnicki, PL
Frederic Allain, CH
Hermona Soreq, IL
Göran Akusjärvi, SE
Gil Ast, IL
Francisco Baralle, IT
Albrecht Bindereif, DE
Daniel Schümperli, CH
Ian Eperon, GB
Christopher Smith, GB
James Stevenin, FR
Juan Valcárcel, ES
Stefan Stamm, DE
Andrea Barta, AT
John W S Brown, GB
Javier Fernando Caceres, GB
Artur Jarmolowski, PL
Angela Krämer, CH
Angus Lain Lamond, GB
Giuseppe Biamonti, IT
Didier Auboeuf, FR
Davide Gabellini, IT
Mihaela Zavolan, CH
Alberto R Kornblihtt, AR
Jamal Tazi, FR
Eduardo Eyras, ES
Diana Baralle, GB
Reinhard Lührmann, DE
 
Project Categories:
Natural Sciences > Aging Diseases and Pathology > Cancer & related diseases > Malignant neoplasms (including in situ)
 
Other Information:
Fiscal Year: 2006
Project Start Date: 1 January 2005
Project End Date: 31 March 2011
Project program: FP6-LIFESCIHEALTH
 
Project Funding Information:
Funding Mechanism: NoE - Network of Excellence
Year Funding Organization Total Funding, $
2006 European Research Council $35,343,000
Project Title: European alternative splicing network of excellence
Project Number: CORDIS-78768
Project web address: Follow on CORDIS
Organization: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften Ev, Germany, Dusseldorf
Collaborators: University Of Southampton, GB
Medical Research Council, GB
European Molecular Biology Laboratory, DE
University Of Edinburgh, GB
Tel Aviv University, IL
Uppsala University, SE
Hebrew University Of Jerusalem, IL
University Of Dundee, GB
University Of Leicester, GB
Medical University Of Vienna, AT
University Of Aarhus, DK
Consiglio Nazionale Delle Ricerche, IT
Centre National De La Recherche Scientifique, FR
The Chancellor, Masters And Scholars Of The University Of Cambridge, GB
Institut National De La Sante Et De La Recherche Medicale, FR
Universite De Geneve, CH
Universität Bern, CH
Fondazione Centro San Raffaele Del Monte Tabor, IT
International Centre For Genetic Engineering And Biotechnology, IT
Universitat Pompeu Fabra, ES
Eidgenoessische Technische Hochschule Zuerich, CH
Scottish Crop Research Institute, GB
Swiss Institute Of Bioinformatics, CH
International Institute Of Molecular And Cell Biology, PL
Centre De Regulació Genòmica, ES
Instituto De Medicina Molecular, PT
Centre Européen De Recherche En Biologie Et Médecine - Groupement D'Intérêt Economique, FR
Unversidad De Buenos Aires, AR
Principal Investigators (PI): Jean Beggs, GB
Peer Bork, DE
Maria Carmo-Fonseca, PT
Jorgen Kjems, DK
Janusz Bujnicki, PL
Frederic Allain, CH
Hermona Soreq, IL
Göran Akusjärvi, SE
Gil Ast, IL
Francisco Baralle, IT
Albrecht Bindereif, DE
Daniel Schümperli, CH
Ian Eperon, GB
Christopher Smith, GB
James Stevenin, FR
Juan Valcárcel, ES
Stefan Stamm, DE
Andrea Barta, AT
John W S Brown, GB
Javier Fernando Caceres, GB
Artur Jarmolowski, PL
Angela Krämer, CH
Angus Lain Lamond, GB
Giuseppe Biamonti, IT
Didier Auboeuf, FR
Davide Gabellini, IT
Mihaela Zavolan, CH
Alberto R Kornblihtt, AR
Jamal Tazi, FR
Eduardo Eyras, ES
Diana Baralle, GB
Reinhard Lührmann, DE
 
Title FY Funding
There are no results for this project in database.
Project Title: European alternative splicing network of excellence
Project Number: CORDIS-78768
Project web address: Follow on CORDIS
Organization: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften Ev, Germany, Dusseldorf
Collaborators: University Of Southampton, GB
Medical Research Council, GB
European Molecular Biology Laboratory, DE
University Of Edinburgh, GB
Tel Aviv University, IL
Uppsala University, SE
Hebrew University Of Jerusalem, IL
University Of Dundee, GB
University Of Leicester, GB
Medical University Of Vienna, AT
University Of Aarhus, DK
Consiglio Nazionale Delle Ricerche, IT
Centre National De La Recherche Scientifique, FR
The Chancellor, Masters And Scholars Of The University Of Cambridge, GB
Institut National De La Sante Et De La Recherche Medicale, FR
Universite De Geneve, CH
Universität Bern, CH
Fondazione Centro San Raffaele Del Monte Tabor, IT
International Centre For Genetic Engineering And Biotechnology, IT
Universitat Pompeu Fabra, ES
Eidgenoessische Technische Hochschule Zuerich, CH
Scottish Crop Research Institute, GB
Swiss Institute Of Bioinformatics, CH
International Institute Of Molecular And Cell Biology, PL
Centre De Regulació Genòmica, ES
Instituto De Medicina Molecular, PT
Centre Européen De Recherche En Biologie Et Médecine - Groupement D'Intérêt Economique, FR
Unversidad De Buenos Aires, AR
Principal Investigators (PI): Jean Beggs, GB
Peer Bork, DE
Maria Carmo-Fonseca, PT
Jorgen Kjems, DK
Janusz Bujnicki, PL
Frederic Allain, CH
Hermona Soreq, IL
Göran Akusjärvi, SE
Gil Ast, IL
Francisco Baralle, IT
Albrecht Bindereif, DE
Daniel Schümperli, CH
Ian Eperon, GB
Christopher Smith, GB
James Stevenin, FR
Juan Valcárcel, ES
Stefan Stamm, DE
Andrea Barta, AT
John W S Brown, GB
Javier Fernando Caceres, GB
Artur Jarmolowski, PL
Angela Krämer, CH
Angus Lain Lamond, GB
Giuseppe Biamonti, IT
Didier Auboeuf, FR
Davide Gabellini, IT
Mihaela Zavolan, CH
Alberto R Kornblihtt, AR
Jamal Tazi, FR
Eduardo Eyras, ES
Diana Baralle, GB
Reinhard Lührmann, DE
 
Project Title Organization FY Funding
European Alternative Splicing Network Of ExcellenceMax-Planck-Gesellschaft Zur Förderung Der Wissenschaften Ev2006$35,343,000
Project Title: European alternative splicing network of excellence
Project Number: CORDIS-78768
Project web address: Follow on CORDIS
Organization: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften Ev, Germany, Dusseldorf
Collaborators: University Of Southampton, GB
Medical Research Council, GB
European Molecular Biology Laboratory, DE
University Of Edinburgh, GB
Tel Aviv University, IL
Uppsala University, SE
Hebrew University Of Jerusalem, IL
University Of Dundee, GB
University Of Leicester, GB
Medical University Of Vienna, AT
University Of Aarhus, DK
Consiglio Nazionale Delle Ricerche, IT
Centre National De La Recherche Scientifique, FR
The Chancellor, Masters And Scholars Of The University Of Cambridge, GB
Institut National De La Sante Et De La Recherche Medicale, FR
Universite De Geneve, CH
Universität Bern, CH
Fondazione Centro San Raffaele Del Monte Tabor, IT
International Centre For Genetic Engineering And Biotechnology, IT
Universitat Pompeu Fabra, ES
Eidgenoessische Technische Hochschule Zuerich, CH
Scottish Crop Research Institute, GB
Swiss Institute Of Bioinformatics, CH
International Institute Of Molecular And Cell Biology, PL
Centre De Regulació Genòmica, ES
Instituto De Medicina Molecular, PT
Centre Européen De Recherche En Biologie Et Médecine - Groupement D'Intérêt Economique, FR
Unversidad De Buenos Aires, AR
Principal Investigators (PI): Jean Beggs, GB
Peer Bork, DE
Maria Carmo-Fonseca, PT
Jorgen Kjems, DK
Janusz Bujnicki, PL
Frederic Allain, CH
Hermona Soreq, IL
Göran Akusjärvi, SE
Gil Ast, IL
Francisco Baralle, IT
Albrecht Bindereif, DE
Daniel Schümperli, CH
Ian Eperon, GB
Christopher Smith, GB
James Stevenin, FR
Juan Valcárcel, ES
Stefan Stamm, DE
Andrea Barta, AT
John W S Brown, GB
Javier Fernando Caceres, GB
Artur Jarmolowski, PL
Angela Krämer, CH
Angus Lain Lamond, GB
Giuseppe Biamonti, IT
Didier Auboeuf, FR
Davide Gabellini, IT
Mihaela Zavolan, CH
Alberto R Kornblihtt, AR
Jamal Tazi, FR
Eduardo Eyras, ES
Diana Baralle, GB
Reinhard Lührmann, DE
 
Project number Project title Principal investigator
There are no any related projects.
Project Title: European alternative splicing network of excellence
Project Number: CORDIS-78768
Project web address: Follow on CORDIS
Organization: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften Ev, Germany, Dusseldorf
Collaborators: University Of Southampton, GB
Medical Research Council, GB
European Molecular Biology Laboratory, DE
University Of Edinburgh, GB
Tel Aviv University, IL
Uppsala University, SE
Hebrew University Of Jerusalem, IL
University Of Dundee, GB
University Of Leicester, GB
Medical University Of Vienna, AT
University Of Aarhus, DK
Consiglio Nazionale Delle Ricerche, IT
Centre National De La Recherche Scientifique, FR
The Chancellor, Masters And Scholars Of The University Of Cambridge, GB
Institut National De La Sante Et De La Recherche Medicale, FR
Universite De Geneve, CH
Universität Bern, CH
Fondazione Centro San Raffaele Del Monte Tabor, IT
International Centre For Genetic Engineering And Biotechnology, IT
Universitat Pompeu Fabra, ES
Eidgenoessische Technische Hochschule Zuerich, CH
Scottish Crop Research Institute, GB
Swiss Institute Of Bioinformatics, CH
International Institute Of Molecular And Cell Biology, PL
Centre De Regulació Genòmica, ES
Instituto De Medicina Molecular, PT
Centre Européen De Recherche En Biologie Et Médecine - Groupement D'Intérêt Economique, FR
Unversidad De Buenos Aires, AR
Principal Investigators (PI): Jean Beggs, GB
Peer Bork, DE
Maria Carmo-Fonseca, PT
Jorgen Kjems, DK
Janusz Bujnicki, PL
Frederic Allain, CH
Hermona Soreq, IL
Göran Akusjärvi, SE
Gil Ast, IL
Francisco Baralle, IT
Albrecht Bindereif, DE
Daniel Schümperli, CH
Ian Eperon, GB
Christopher Smith, GB
James Stevenin, FR
Juan Valcárcel, ES
Stefan Stamm, DE
Andrea Barta, AT
John W S Brown, GB
Javier Fernando Caceres, GB
Artur Jarmolowski, PL
Angela Krämer, CH
Angus Lain Lamond, GB
Giuseppe Biamonti, IT
Didier Auboeuf, FR
Davide Gabellini, IT
Mihaela Zavolan, CH
Alberto R Kornblihtt, AR
Jamal Tazi, FR
Eduardo Eyras, ES
Diana Baralle, GB
Reinhard Lührmann, DE
 
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