Ubiquitous pharmacogenomics (u-pgx): making actionable pharmacogenomic data and effective treatment optimization accessible to every european citizen

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Project Title: Ubiquitous pharmacogenomics (u-pgx): making actionable pharmacogenomic data and effective treatment optimization accessible to every european citizen
Project Number: CORDIS-199754
Project web address: Follow on CORDIS
Organization: Academisch Ziekenhuis Leiden, Netherlands, Leiden
Collaborators: Uppsala University, SE
University Of Liverpool, GB
Karolinska Institutet, SE
Universite Paul Sabatier De Toulouse Iii, FR
Bundesinstitut Fur Arzneimittel Und Medizinprodukte, DE
Servicio Andaluz De Salud, ES
Univerza V Ljubljani, SI
Medizinische Universitaet Wien, AT
Panepistimio Patron, GR
Robert Bosch Gesellschaft Fuer Medizinische Forschung Mbh, DE
Stichting Sint Antonius Ziekenhuis, NL
Centro Di Riferimento Oncologico Di Aviano, IT
Bio.Logis Genetic Information Management Gmbh, DE
The Golden Helix Foundation, GB
Knmp Holding B.V., NL
 
Project Description:
Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and embedded into the patients’ electronic record) of a panel of important pharmacogenomic variants as a new model of personalised medicine. To meet this goal we combine existing pharmacogenomics guidelines and novel health IT solutions. Implementation will be conducted at a large scale in seven existing European health care environments and accounts for the diversity in health system organisations and settings. Feasibility, health outcome and cost-effectiveness will be investigated. We will formulate European strategies for improving clinical implementation of pharmacogenomics based on the findings of this project.
 
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Project Title: Ubiquitous pharmacogenomics (u-pgx): making actionable pharmacogenomic data and effective treatment optimization accessible to every european citizen
Project Number: CORDIS-199754
Project web address: Follow on CORDIS
Organization: Academisch Ziekenhuis Leiden, Netherlands, Leiden
Collaborators: Uppsala University, SE
University Of Liverpool, GB
Karolinska Institutet, SE
Universite Paul Sabatier De Toulouse Iii, FR
Bundesinstitut Fur Arzneimittel Und Medizinprodukte, DE
Servicio Andaluz De Salud, ES
Univerza V Ljubljani, SI
Medizinische Universitaet Wien, AT
Panepistimio Patron, GR
Robert Bosch Gesellschaft Fuer Medizinische Forschung Mbh, DE
Stichting Sint Antonius Ziekenhuis, NL
Centro Di Riferimento Oncologico Di Aviano, IT
Bio.Logis Genetic Information Management Gmbh, DE
The Golden Helix Foundation, GB
Knmp Holding B.V., NL
 
Project Categories:
Natural Sciences > Clinical Trials & Therapy > Treatment
 
Other Information:
Fiscal Year: 2016
Project Start Date: 1 January 2015
Project End Date: 31 December 2020
Project program: H2020-EU.3.1.
 
Project Funding Information:
Funding Mechanism: RIA - Research and Innovation action
Year Funding Organization Total Funding, $
2016 European Research Council $16,430,275