Epic-cvd: individualised cvd risk assessment: tailoring targeted and cost-effective approaches to europe's diverse populations

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Project Title: Epic-cvd: individualised cvd risk assessment: tailoring targeted and cost-effective approaches to europe's diverse populations
Project Number: CORDIS-102241
Project web address: Follow on CORDIS
Organization: The Chancellor, Masters And Scholars Of The University Of Cambridge, United Kingdom, Cambridge
Collaborators: Medical Research Council, GB
Lund University, SE
University Of Auckland, NZ
Umea University, SE
Imperial College Of Science, Technology And Medicine, GB
The Chancellor, Masters And Scholars Of The University Of Oxford, GB
Aarhus Universitet, DK
Università Degli Studi Di Napoli Federico Ii, IT
Deutsches Krebsforschungszentrum, DE
Centre International De Recherche Sur Le Cancer, FR
Universitair Medisch Centrum Utrecht, NL
Fundacion Para La Formacion E Investigacion Sanitarias De La Region De Murcia, ES
Deutsches Institut Fuer Ernaehrungsforschung, Potsdam-Rehbruecke, DE
Fondazione Irccs Istituto Nazionale Dei Tumori, IT
Rijksinstituut Voor Volksgezondheid En Milieu, NL
Istituto Per Lo Studio E La Prevenzione Oncologica, IT
Universitetet I Tromsoe, NO
Rand Europe Community Interest Company, GB
Hellenic Health Foundation, GR
Foundation For Genomics & Population Health, GB
Asociacion Instituto Biodonostia, ES
Vitas As, NO
Escuela Andaluza De Salud Publica Sa, ES
Consejeria De Salud Y Servicios Sanitarios - Principado De Asturias, ES
Brainshake Oy, FI
Fundacion Publica Miguel Servet, ES
Human Genetics Foundation, IT
Associazione Iblea Per La Ricerca Epidemiologica Onlus, IT
Organismo Autonomo Instituto De Salud Publica Y Laboral De Navarra, ES
Principal Investigators (PI): Göran Hallmans, SE
Domenico Palli, IT
Nick Wareham, GB
Salvatore Panico, IT
Heiner Boeing, DE
Olle Melander, SE
Tatjana Palalic, GB
Ina Krischek, DE
Eiliv Lund, NO
Antonia Trichopoulou, GR
Irune Vegas, ES
Kate Harrower, NZ
Carmen Navarro, ES
Ellen Nolte, GB
Sánchez-Pérez María-José, ES
Laudina Rodriguez, ES
Tim Key, GB
Hilary Burton, GB
Dorthe Hejl Boye, DK
Suna Teemu, FI
Conchi Moreno-Iribas, ES
Thomas Gundersen, NO
Yvonne Van Der Schouw, NL
Maimuna Mendy, FR
Giuseppe Matullo, IT
Francesco Occhipinti, IT
Jolanda Maria Antoinette Boer, NL
Marisol Fragoso, ES
Vittorio Krogh, IT
John Danesh, GB
 
Project Description:
EPIC-CVD's overarching goal is to provide clinicians and policy-makers with a menu of evidence-based options for cost-effective individualised risk assessment that enables the EU's increasingly resource-constrained economies to achieve more personalised predictive medicine in harmony with Europe's diverse cultures and healthcare systems.We will achieve this through developing and validating innovative risk scores and efficient screening strategies by studying 75 high priority soluble biomarkers and 215,000 carefully selected genetic variants in the most powerful population-based prospective study ever conducted of incident coronary heart disease, stroke, and type 2 diabetes across 10 diverse European countries. EPIC-CVD will provide the first consideration across Europe of risk scores with information on the interplay of nature and nurture together with biomarkers of lifestyle, biological pathways, vascular injury, and ageing.Our multidisciplinary consortium involves world-leading expertise in population health science, laboratory science (including VITAS, an SME partner, renowned for nutritional biomarker assays), translational science, and implementation science. This rare combination of expertise will enable systematic consideration of the implications of risk scores and screening strategies for predictive accuracy, feasibility, safety, acceptability, and cost-effectiveness. The impact on clinical decision making and clinical outcomes will be demonstrated in a new randomised trial of risk scores in relation to ""patient-centred"" outcomes that assess attitudes, behaviours, and biological risk factors.Key stakeholders (eg, healthcare professionals, regulators, industry) will be closely engaged by the project. Policy recommendations mindful of the broader societal implications of targeted screening will be tailored to Europe's diverse needs and systematically disseminated to various audiences. This initiative will derive major synergy from related efforts.
 
Project Terms:
life sciences
Project Title: Epic-cvd: individualised cvd risk assessment: tailoring targeted and cost-effective approaches to europe's diverse populations
Project Number: CORDIS-102241
Project web address: Follow on CORDIS
Organization: The Chancellor, Masters And Scholars Of The University Of Cambridge, United Kingdom, Cambridge
Collaborators: Medical Research Council, GB
Lund University, SE
University Of Auckland, NZ
Umea University, SE
Imperial College Of Science, Technology And Medicine, GB
The Chancellor, Masters And Scholars Of The University Of Oxford, GB
Aarhus Universitet, DK
Università Degli Studi Di Napoli Federico Ii, IT
Deutsches Krebsforschungszentrum, DE
Centre International De Recherche Sur Le Cancer, FR
Universitair Medisch Centrum Utrecht, NL
Fundacion Para La Formacion E Investigacion Sanitarias De La Region De Murcia, ES
Deutsches Institut Fuer Ernaehrungsforschung, Potsdam-Rehbruecke, DE
Fondazione Irccs Istituto Nazionale Dei Tumori, IT
Rijksinstituut Voor Volksgezondheid En Milieu, NL
Istituto Per Lo Studio E La Prevenzione Oncologica, IT
Universitetet I Tromsoe, NO
Rand Europe Community Interest Company, GB
Hellenic Health Foundation, GR
Foundation For Genomics & Population Health, GB
Asociacion Instituto Biodonostia, ES
Vitas As, NO
Escuela Andaluza De Salud Publica Sa, ES
Consejeria De Salud Y Servicios Sanitarios - Principado De Asturias, ES
Brainshake Oy, FI
Fundacion Publica Miguel Servet, ES
Human Genetics Foundation, IT
Associazione Iblea Per La Ricerca Epidemiologica Onlus, IT
Organismo Autonomo Instituto De Salud Publica Y Laboral De Navarra, ES
Principal Investigators (PI): Göran Hallmans, SE
Domenico Palli, IT
Nick Wareham, GB
Salvatore Panico, IT
Heiner Boeing, DE
Olle Melander, SE
Tatjana Palalic, GB
Ina Krischek, DE
Eiliv Lund, NO
Antonia Trichopoulou, GR
Irune Vegas, ES
Kate Harrower, NZ
Carmen Navarro, ES
Ellen Nolte, GB
Sánchez-Pérez María-José, ES
Laudina Rodriguez, ES
Tim Key, GB
Hilary Burton, GB
Dorthe Hejl Boye, DK
Suna Teemu, FI
Conchi Moreno-Iribas, ES
Thomas Gundersen, NO
Yvonne Van Der Schouw, NL
Maimuna Mendy, FR
Giuseppe Matullo, IT
Francesco Occhipinti, IT
Jolanda Maria Antoinette Boer, NL
Marisol Fragoso, ES
Vittorio Krogh, IT
John Danesh, GB
 
Project Categories:
Natural Sciences > Aging Diseases and Pathology > Cardiovascular and cerebrovascular diseases
 
Other Information:
Fiscal Year: 2012
Project Start Date: 1 January 2011
Project End Date: 31 December 2015
Project program: FP7-HEALTH
 
Project Funding Information:
Funding Mechanism: CP-FP - Small or medium-scale focused research project
Year Funding Organization Total Funding, $
2012 European Research Council $8,742,363
Project Title: Epic-cvd: individualised cvd risk assessment: tailoring targeted and cost-effective approaches to europe's diverse populations
Project Number: CORDIS-102241
Project web address: Follow on CORDIS
Organization: The Chancellor, Masters And Scholars Of The University Of Cambridge, United Kingdom, Cambridge
Collaborators: Medical Research Council, GB
Lund University, SE
University Of Auckland, NZ
Umea University, SE
Imperial College Of Science, Technology And Medicine, GB
The Chancellor, Masters And Scholars Of The University Of Oxford, GB
Aarhus Universitet, DK
Università Degli Studi Di Napoli Federico Ii, IT
Deutsches Krebsforschungszentrum, DE
Centre International De Recherche Sur Le Cancer, FR
Universitair Medisch Centrum Utrecht, NL
Fundacion Para La Formacion E Investigacion Sanitarias De La Region De Murcia, ES
Deutsches Institut Fuer Ernaehrungsforschung, Potsdam-Rehbruecke, DE
Fondazione Irccs Istituto Nazionale Dei Tumori, IT
Rijksinstituut Voor Volksgezondheid En Milieu, NL
Istituto Per Lo Studio E La Prevenzione Oncologica, IT
Universitetet I Tromsoe, NO
Rand Europe Community Interest Company, GB
Hellenic Health Foundation, GR
Foundation For Genomics & Population Health, GB
Asociacion Instituto Biodonostia, ES
Vitas As, NO
Escuela Andaluza De Salud Publica Sa, ES
Consejeria De Salud Y Servicios Sanitarios - Principado De Asturias, ES
Brainshake Oy, FI
Fundacion Publica Miguel Servet, ES
Human Genetics Foundation, IT
Associazione Iblea Per La Ricerca Epidemiologica Onlus, IT
Organismo Autonomo Instituto De Salud Publica Y Laboral De Navarra, ES
Principal Investigators (PI): Göran Hallmans, SE
Domenico Palli, IT
Nick Wareham, GB
Salvatore Panico, IT
Heiner Boeing, DE
Olle Melander, SE
Tatjana Palalic, GB
Ina Krischek, DE
Eiliv Lund, NO
Antonia Trichopoulou, GR
Irune Vegas, ES
Kate Harrower, NZ
Carmen Navarro, ES
Ellen Nolte, GB
Sánchez-Pérez María-José, ES
Laudina Rodriguez, ES
Tim Key, GB
Hilary Burton, GB
Dorthe Hejl Boye, DK
Suna Teemu, FI
Conchi Moreno-Iribas, ES
Thomas Gundersen, NO
Yvonne Van Der Schouw, NL
Maimuna Mendy, FR
Giuseppe Matullo, IT
Francesco Occhipinti, IT
Jolanda Maria Antoinette Boer, NL
Marisol Fragoso, ES
Vittorio Krogh, IT
John Danesh, GB
 
Title FY Funding
There are no results for this project in database.
Project Title: Epic-cvd: individualised cvd risk assessment: tailoring targeted and cost-effective approaches to europe's diverse populations
Project Number: CORDIS-102241
Project web address: Follow on CORDIS
Organization: The Chancellor, Masters And Scholars Of The University Of Cambridge, United Kingdom, Cambridge
Collaborators: Medical Research Council, GB
Lund University, SE
University Of Auckland, NZ
Umea University, SE
Imperial College Of Science, Technology And Medicine, GB
The Chancellor, Masters And Scholars Of The University Of Oxford, GB
Aarhus Universitet, DK
Università Degli Studi Di Napoli Federico Ii, IT
Deutsches Krebsforschungszentrum, DE
Centre International De Recherche Sur Le Cancer, FR
Universitair Medisch Centrum Utrecht, NL
Fundacion Para La Formacion E Investigacion Sanitarias De La Region De Murcia, ES
Deutsches Institut Fuer Ernaehrungsforschung, Potsdam-Rehbruecke, DE
Fondazione Irccs Istituto Nazionale Dei Tumori, IT
Rijksinstituut Voor Volksgezondheid En Milieu, NL
Istituto Per Lo Studio E La Prevenzione Oncologica, IT
Universitetet I Tromsoe, NO
Rand Europe Community Interest Company, GB
Hellenic Health Foundation, GR
Foundation For Genomics & Population Health, GB
Asociacion Instituto Biodonostia, ES
Vitas As, NO
Escuela Andaluza De Salud Publica Sa, ES
Consejeria De Salud Y Servicios Sanitarios - Principado De Asturias, ES
Brainshake Oy, FI
Fundacion Publica Miguel Servet, ES
Human Genetics Foundation, IT
Associazione Iblea Per La Ricerca Epidemiologica Onlus, IT
Organismo Autonomo Instituto De Salud Publica Y Laboral De Navarra, ES
Principal Investigators (PI): Göran Hallmans, SE
Domenico Palli, IT
Nick Wareham, GB
Salvatore Panico, IT
Heiner Boeing, DE
Olle Melander, SE
Tatjana Palalic, GB
Ina Krischek, DE
Eiliv Lund, NO
Antonia Trichopoulou, GR
Irune Vegas, ES
Kate Harrower, NZ
Carmen Navarro, ES
Ellen Nolte, GB
Sánchez-Pérez María-José, ES
Laudina Rodriguez, ES
Tim Key, GB
Hilary Burton, GB
Dorthe Hejl Boye, DK
Suna Teemu, FI
Conchi Moreno-Iribas, ES
Thomas Gundersen, NO
Yvonne Van Der Schouw, NL
Maimuna Mendy, FR
Giuseppe Matullo, IT
Francesco Occhipinti, IT
Jolanda Maria Antoinette Boer, NL
Marisol Fragoso, ES
Vittorio Krogh, IT
John Danesh, GB
 
Project Title Organization FY Funding
Epic-Cvd: Individualised Cvd Risk Assessment: Tailoring Targeted And Cost-Effective Approaches To Europe'S Diverse PopulationsThe Chancellor, Masters And Scholars Of The University Of Cambridge2012$8,742,363
Project Title: Epic-cvd: individualised cvd risk assessment: tailoring targeted and cost-effective approaches to europe's diverse populations
Project Number: CORDIS-102241
Project web address: Follow on CORDIS
Organization: The Chancellor, Masters And Scholars Of The University Of Cambridge, United Kingdom, Cambridge
Collaborators: Medical Research Council, GB
Lund University, SE
University Of Auckland, NZ
Umea University, SE
Imperial College Of Science, Technology And Medicine, GB
The Chancellor, Masters And Scholars Of The University Of Oxford, GB
Aarhus Universitet, DK
Università Degli Studi Di Napoli Federico Ii, IT
Deutsches Krebsforschungszentrum, DE
Centre International De Recherche Sur Le Cancer, FR
Universitair Medisch Centrum Utrecht, NL
Fundacion Para La Formacion E Investigacion Sanitarias De La Region De Murcia, ES
Deutsches Institut Fuer Ernaehrungsforschung, Potsdam-Rehbruecke, DE
Fondazione Irccs Istituto Nazionale Dei Tumori, IT
Rijksinstituut Voor Volksgezondheid En Milieu, NL
Istituto Per Lo Studio E La Prevenzione Oncologica, IT
Universitetet I Tromsoe, NO
Rand Europe Community Interest Company, GB
Hellenic Health Foundation, GR
Foundation For Genomics & Population Health, GB
Asociacion Instituto Biodonostia, ES
Vitas As, NO
Escuela Andaluza De Salud Publica Sa, ES
Consejeria De Salud Y Servicios Sanitarios - Principado De Asturias, ES
Brainshake Oy, FI
Fundacion Publica Miguel Servet, ES
Human Genetics Foundation, IT
Associazione Iblea Per La Ricerca Epidemiologica Onlus, IT
Organismo Autonomo Instituto De Salud Publica Y Laboral De Navarra, ES
Principal Investigators (PI): Göran Hallmans, SE
Domenico Palli, IT
Nick Wareham, GB
Salvatore Panico, IT
Heiner Boeing, DE
Olle Melander, SE
Tatjana Palalic, GB
Ina Krischek, DE
Eiliv Lund, NO
Antonia Trichopoulou, GR
Irune Vegas, ES
Kate Harrower, NZ
Carmen Navarro, ES
Ellen Nolte, GB
Sánchez-Pérez María-José, ES
Laudina Rodriguez, ES
Tim Key, GB
Hilary Burton, GB
Dorthe Hejl Boye, DK
Suna Teemu, FI
Conchi Moreno-Iribas, ES
Thomas Gundersen, NO
Yvonne Van Der Schouw, NL
Maimuna Mendy, FR
Giuseppe Matullo, IT
Francesco Occhipinti, IT
Jolanda Maria Antoinette Boer, NL
Marisol Fragoso, ES
Vittorio Krogh, IT
John Danesh, GB
 
Project number Project title Principal investigator
There are no any related projects.
Project Title: Epic-cvd: individualised cvd risk assessment: tailoring targeted and cost-effective approaches to europe's diverse populations
Project Number: CORDIS-102241
Project web address: Follow on CORDIS
Organization: The Chancellor, Masters And Scholars Of The University Of Cambridge, United Kingdom, Cambridge
Collaborators: Medical Research Council, GB
Lund University, SE
University Of Auckland, NZ
Umea University, SE
Imperial College Of Science, Technology And Medicine, GB
The Chancellor, Masters And Scholars Of The University Of Oxford, GB
Aarhus Universitet, DK
Università Degli Studi Di Napoli Federico Ii, IT
Deutsches Krebsforschungszentrum, DE
Centre International De Recherche Sur Le Cancer, FR
Universitair Medisch Centrum Utrecht, NL
Fundacion Para La Formacion E Investigacion Sanitarias De La Region De Murcia, ES
Deutsches Institut Fuer Ernaehrungsforschung, Potsdam-Rehbruecke, DE
Fondazione Irccs Istituto Nazionale Dei Tumori, IT
Rijksinstituut Voor Volksgezondheid En Milieu, NL
Istituto Per Lo Studio E La Prevenzione Oncologica, IT
Universitetet I Tromsoe, NO
Rand Europe Community Interest Company, GB
Hellenic Health Foundation, GR
Foundation For Genomics & Population Health, GB
Asociacion Instituto Biodonostia, ES
Vitas As, NO
Escuela Andaluza De Salud Publica Sa, ES
Consejeria De Salud Y Servicios Sanitarios - Principado De Asturias, ES
Brainshake Oy, FI
Fundacion Publica Miguel Servet, ES
Human Genetics Foundation, IT
Associazione Iblea Per La Ricerca Epidemiologica Onlus, IT
Organismo Autonomo Instituto De Salud Publica Y Laboral De Navarra, ES
Principal Investigators (PI): Göran Hallmans, SE
Domenico Palli, IT
Nick Wareham, GB
Salvatore Panico, IT
Heiner Boeing, DE
Olle Melander, SE
Tatjana Palalic, GB
Ina Krischek, DE
Eiliv Lund, NO
Antonia Trichopoulou, GR
Irune Vegas, ES
Kate Harrower, NZ
Carmen Navarro, ES
Ellen Nolte, GB
Sánchez-Pérez María-José, ES
Laudina Rodriguez, ES
Tim Key, GB
Hilary Burton, GB
Dorthe Hejl Boye, DK
Suna Teemu, FI
Conchi Moreno-Iribas, ES
Thomas Gundersen, NO
Yvonne Van Der Schouw, NL
Maimuna Mendy, FR
Giuseppe Matullo, IT
Francesco Occhipinti, IT
Jolanda Maria Antoinette Boer, NL
Marisol Fragoso, ES
Vittorio Krogh, IT
John Danesh, GB
 
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