Loc: hiv prevention trials network

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Project Title: Loc: hiv prevention trials network
Project Number: 5UM1AI068619-09
Project web address: Follow on NIH
Organization: Family Health International, United States, North Carolina, RESEARCH TRIANGLE PARK
Principal Investigators (PI): El-Sadr Wafaa M, US
Cohen Myron S, US
 
Project Description:
The mission of the HIV Prevention Trials Network (HPTN) is to conduct research designed to identify the best combinations of HIV prevention interventions to prevent HIV infection in populations at the highest risk for this infection. The HPTN will be led by Drs. Wafaa EI-Sadr, Columbia University, and Myron S. Cohen, University of North Carolina at Chapel Hill, and supported by experienced operations, laboratory and statistical and data centers. The HPTN will address and support the two research Priority Areas in order to achieve the following eight Specific Aims: Specific Aims for Priority Area 1: Integrate Strategies to Prevent HIV Infection: Aim 1: To develop an integrated strategy to prevent HIV infection in young women in Southern Africa; Aim 2: To develop integrated strategies to prevent HIV infection in men who have sex with men (MSM); Sub-aim 2a: To identify an integrated strategy to prevent HIV acquisition in HIV-uninfected MSM and transgender women in the Americas; Sub-aim 2b: To identify an integrated strategy to prevent HIV transmission from HIV-infected MSM in the United States (U.S.); Aim 3: To develop an integrated strategy to prevent HIV infection in injection drug users (IDUs) in Eastern Europe and Asia; Aim 4: To implement an integrated strategy to virtually eliminate (<1%) HIV transmission in discordant couples in sub-Saharan Africa {SSA}; Aim 5: To develop methods to engage MSM in SSA in prevention research, paving the way for development of an integrated strategy to prevent HIV infection in this population Specific Aims for Priority Area 2: Pre-exposure Prophylaxis {PrEP}: Aim 6: To evaluate the efficacy of an ARV regimen containing maraviroc (MVC) for PrEP; Aim 7: To develop new agents for PrEP with favorable profiles, including long lasting agents; Aim 8: To develop pharmacostatistical models to define the role of new agents for PrEP. RELEVANCE: The research proposed by the HIV Prevention Trials Network (HPTN) aims to combine known interventions and identify new ones to stop the transmission of HIV infection with the goal of inspiring changes in public health policy and practice, and to ending the HIV epidemic.
 
Project Terms:
address africa south of the sahara aids prevention americas area couples data development eastern europe epidemic experience far east goals health policy health practice high risk hiv hiv infections hiv prevention trials network infection injecting drug user intervention laboratories men who have sex with men methods mission modeling myron new agents north carolina operation population prevent prevention research preventive intervention prophylactic treatment public health regimen research research design research priority role southern africa transgender women transmission process united states universities young woman behavioral and social science clinical research clinical trials and supportive activities drug abuse (nida only) hiv/aids infectious diseases prevention sexual and gender minorities (sgm/lgbt*) substance abuse
Project Title: Loc: hiv prevention trials network
Project Number: 5UM1AI068619-09
Project web address: Follow on NIH
Organization: Family Health International, United States, North Carolina, RESEARCH TRIANGLE PARK
Principal Investigators (PI): El-Sadr Wafaa M, US
Cohen Myron S, US
 
Project Categories:
Behavioral and Social Sciences > Population studies
 
Other Information:
Fiscal Year: 2006
Project Start Date: 1 June 2006
Project End Date: 30 November 2020
Project program: Research Project with Complex Structure Cooperative Agreement
 
Project Funding Information:
Funding Mechanism: Non-SBIR/STTR RPGs
Year Funding Organization Total Funding, $
2015 NIH - National Institute Of Allergy And Infectious Diseases $23,261,055
Project Title: Loc: hiv prevention trials network
Project Number: 5UM1AI068619-09
Project web address: Follow on NIH
Organization: Family Health International, United States, North Carolina, RESEARCH TRIANGLE PARK
Principal Investigators (PI): El-Sadr Wafaa M, US
Cohen Myron S, US
 
Title FY Funding
There are no results for this project in database.
Project Title: Loc: hiv prevention trials network
Project Number: 5UM1AI068619-09
Project web address: Follow on NIH
Organization: Family Health International, United States, North Carolina, RESEARCH TRIANGLE PARK
Principal Investigators (PI): El-Sadr Wafaa M, US
Cohen Myron S, US
 
Project number Project title Principal investigator
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Project Title: Loc: hiv prevention trials network
Project Number: 5UM1AI068619-09
Project web address: Follow on NIH
Organization: Family Health International, United States, North Carolina, RESEARCH TRIANGLE PARK
Principal Investigators (PI): El-Sadr Wafaa M, US
Cohen Myron S, US
 
Title Journal Year Country Rel
Venues for Meeting Sex Partners and Partner HIV Risk Characteristics: HIV Prevention Trials Network (HPTN064) Women's HIV Seroincidence Study (ISIS). AIDS Behav 2016 united states
Antiretroviral Medication Adherence and Amplified HIV Transmission Risk Among Sexually Active HIV-Infected Individuals in Three Diverse International Settings. AIDS Behav 2016 united states
Brief Report: HIV Drug Resistance in Adults Failing Early Antiretroviral Treatment: Results From the HIV Prevention Trials Network 052 Trial. J Acquir Immune Defic Syndr 2016 united states
Socioecological factors influencing women's HIV risk in the United States: qualitative findings from the women's HIV SeroIncidence study (HPTN 064). BMC Public Health 2016 england
Using Cognitive Interviews to Enhance Measurement in Empirical Bioethics: Developing a Measure of the Preventive Misconception in Biomedical HIV Prevention Trials. AJOB Empir Bioeth 2016 united states
Economic Resources and HIV Preventive Behaviors Among School-Enrolled Young Women in Rural South Africa (HPTN 068). AIDS Behav 2016 united states
Transgender Women in Clinical Trials of Pre-Exposure Prophylaxis. J Acquir Immune Defic Syndr 2016 united states