Center for genome research

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Project Title: Center for genome research
Principal Investigators (PI): LANDER ERIC S
Project Number: 5U54HG002045-03
Organization: WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
 
Project Description:
Under NHGRI's sequencing pilot project, the Whitehead/MIT Center for Genome Research has developed a scalable and efficient process for genomic sequencing. The specific aim of this proposal is to convert our pilot project to a production center by: (i) increasing lane capacity to 20 M lanes per year, by expanding our automated systems for sample prep and purchasing a fleet of capillary sequencers; and (ii) achieving a production rate of finished sequence of at least 750 Mb per year at a cost of 10 cents/base including overhead. We are also committed to working closely with NHGRI and other centers to adapt to rapidly changing circumstances, to ensure the overall rapid success of the Human Genome Project.
 
Project Terms:
genetic techniques technology /technique development nucleic acid sequence genome genetic mapping computer assisted sequence analysis biomedical automation cooperative study computer program /software robotics human genetic material tag
Project Title: Center for genome research
Principal Investigators (PI): LANDER ERIC S
Project Number: 5U54HG002045-03
Organization: WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
 
Project Categories:
Natural Sciences > Experimental techniques > in vitro methods > Genomic analys
 
Other Information:
Fiscal Year: 1999
Project Start Date: 8 March 1999
Project End Date: 31 October 2003
Administering Institute Or Center: HG
 
Project Funding Information:
Total Funding: $57,896,226
Total Cost: $57,896,226
Year Funding Organization Total Funding, $
2001 NATIONAL HUMAN GENOME RESEARCH INSTITUTE $57,896,226
Project Title: Center for genome research
Principal Investigators (PI): LANDER ERIC S
Project Number: 5U54HG002045-03
Organization: WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
 
Project_number Title Year FY Total Cost
There are no results for this project in database.
Project Title: Center for genome research
Principal Investigators (PI): LANDER ERIC S
Project Number: 5U54HG002045-03
Organization: WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
 
Project number Project title Organization FY Funding Organization FY Total Cost
5U54HG002152-05SEQUENCING THE MOUSE GENOMEWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2003NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$9,125,000
5U54HG002045-05CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2003NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$59,823,750
3U54HG002045-05S1CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2003NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$3,268,176
3U54HG002152-04S1SEQUENCING THE MOUSE GENOMEWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2002NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$4,323,000
5U54HG002152-04SEQUENCING THE MOUSE GENOMEWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2002NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$6,511,647
3U54HG002045-04S1CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2002NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$56,525
5U54HG002045-04CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2002NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$54,893,719
3U54HG002045-03S2CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2002NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$4,938,826
3U54HG002045-04S2CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2002NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$589,825
3U54HG002152-03S1SEQUENCING THE MOUSE GENOMEWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2001NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$12,716,036
5U54HG002152-03SEQUENCING THE MOUSE GENOMEWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2001NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$5,473,864
3U54HG002045-03S1CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2001NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$20,314
5U54HG002045-03CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2001NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$57,896,226
5R01HG001953-03SINGLE NUCLEOTIDE POLYMORPHISMS IN GENE CODING REGIONSWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2001NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$2,245,054
5U54HG002152-02SEQUENCING THE MOUSE GENOMEWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2000NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$4,308,317
5U54HG002045-02CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2000NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$53,354,001
3U54HG002045-02S1CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2000NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$15,500
3U54HG002045-02S2CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2000NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$5,000,000
3U54HG002045-02S3CENTER FOR GENOME RESEARCHWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2000NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$308,508
5R01HG001953-02SINGLE NUCLEOTIDE POLYMORPHISMS IN GENE CODING REGIONSWHITEHEAD INSTITUTE FOR BIOMEDICAL RES2000NATIONAL HUMAN GENOME RESEARCH INSTITUTE
$2,268,766
Project Title: Center for genome research
Principal Investigators (PI): LANDER ERIC S
Project Number: 5U54HG002045-03
Organization: WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
 
Project number Project title Principal investigator
There are no any related projects.
Project Title: Center for genome research
Principal Investigators (PI): LANDER ERIC S
Project Number: 5U54HG002045-03
Organization: WHITEHEAD INSTITUTE FOR BIOMEDICAL RES
 
Title Abstract Authors Year Rel
Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs. Genome research.. 2002 May 12 (5) :729-38 Park, Sung-Sup; Stankiewicz, Pawel; Bi, Weimin; Shaw, Christine; Lehoczky, Jessica; Dewar, Ken; Birren, Bruce; Lupski, James R 2002
RIP: the evolutionary cost of genome defense. Trends in genetics : TIG.. 2004 Sep 20 (9) :417-23 Galagan, James E; Selker, Eric U 2004
The genetic landscape of high-risk neuroblastoma. Nature genetics. 2013 Mar 45 (3) :279-84 Pugh, Trevor J;Morozova, Olena;Attiyeh, Edward F;Asgharzadeh, Shahab;Wei, Jun S;Auclair, Daniel;Carter, Scott L;Cibulskis, Kristian;Hanna, Megan;Kiezun, Adam;Kim, Jaegil;Lawrence, Michael S;Lichenstein, Lee;McKenna, Aaron;Pedamallu, Chandra Sekhar;Ramos, Alex H;Shefler, Erica;Sivachenko, Andrey;Sougnez, Carrie;Stewart, Chip;Ally, Adrian;Birol, Inanc;Chiu, Readman;Corbett, Richard D;Hirst, Martin;Jackman, Shaun D;Kamoh, Baljit;Khodabakshi, Alireza Hadj;Krzywinski, Martin;Lo, Allan;Moore, Richard A;Mungall, Karen L;Qian, Jenny;Tam, Angela;Thiessen, Nina;Zhao, Yongjun;Cole, Kristina A;Diamond, Maura;Diskin, Sharon J;Mosse, Yael P;Wood, Andrew C;Ji, Lingyun;Sposto, Richard;Badgett, Thomas;London, Wendy B;Moyer, Yvonne;Gastier-Foster, Julie M;Smith, Malcolm A;Auvil, Jaime M Guidry;Gerhard, Daniela S;Hogarty, Michael D;Jones, Steven J M;Lander, Eric S;Gabriel, Stacey B;Getz, Gad;Seeger, Robert C;Khan, Javed;Marra, Marco A;Meyerson, Matthew;Maris, John M 2013
The genomic substrate for adaptive radiation in African cichlid fish. Nature. 2014 Sep 18 513 (7518) :375-81 Brawand, David;Wagner, Catherine E;Li, Yang I;Malinsky, Milan;Keller, Irene;Fan, Shaohua;Simakov, Oleg;Ng, Alvin Y;Lim, Zhi Wei;Bezault, Etienne;Turner-Maier, Jason;Johnson, Jeremy;Alcazar, Rosa;Noh, Hyun Ji;Russell, Pamela;Aken, Bronwen;Alfoldi, Jessica;Amemiya, Chris;Azzouzi, Naoual;Baroiller, Jean-Francois;Barloy-Hubler, Frederique;Berlin, Aaron;Bloomquist, Ryan;Carleton, Karen L;Conte, Matthew A;D'Cotta, Helena;Eshel, Orly;Gaffney, Leslie;Galibert, Francis;Gante, Hugo F;Gnerre, Sante;Greuter, Lucie;Guyon, Richard;Haddad, Natalie S;Haerty, Wilfried;Harris, Rayna M;Hofmann, Hans A;Hourlier, Thibaut;Hulata, Gideon;Jaffe, David B;Lara, Marcia;Lee, Alison P;MacCallum, Iain;Mwaiko, Salome;Nikaido, Masato;Nishihara, Hidenori;Ozouf-Costaz, Catherine;Penman, David J;Przybylski, Dariusz;Rakotomanga, Michaelle;Renn, Suzy C P;Ribeiro, Filipe J;Ron, Micha;Salzburger, Walter;Sanchez-Pulido, Luis;Santos, M Emilia;Searle, Steve;Sharpe, Ted;Swofford, Ross;Tan, Frederick J;Williams, Louise;Young, Sarah;Yin, Shuangye;Okada, Norihiro;Kocher, Thomas D;Miska, Eric A;Lander, Eric S;Venkatesh, Byrappa;Fernald, Russell D;Meyer, Axel;Ponting, Chris P;Streelman, J Todd;Lindblad-Toh, Kerstin;Seehausen, Ole;Di Palma, Federica 2014