Arra::yes::arra tas::75 0850::tas recovery act - sequencing for the cancer genom

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Project Title: Arra::yes::arra tas::75 0850::tas recovery act - sequencing for the cancer genom
Project Number: 261201000055C-2-0-1
Project web address: Follow on NIH
Organization: Broad Institute, Inc., United States, Massachusetts, CAMBRIDGE
Principal Investigators (PI): Gabriel Stacey, US
 
Project Description:
TCGA has historically relied on retrospectively collected biospecimens. These tissues were accrued by dozens of TSSs around the world through a series of subcontracts managed through the prime contractor at SAIC-Frederick. TSSs included clinical sites, academic institutions as well as commercial companies with biorepositories. Retrospective samples have been invaluable sources of tissue and clinical data, often including long term follow-up. However, the rigorous biospecimen quality, including amount of tissue needed (between 100-150mg), percent of tumor nuclei (at least 70%) and low amount of necrosis (less than 30%) has posed challenges, requiring TCGA to look also at prospective collections. The purpose of this project is to establish Tissue Source Site (TSS) networks capable of delivering clinically annotated biospecimens through either/both retrospective and prospective collections. The tissues and clinical data will be delivered to one of TCGAs Biospecimen Core Resource(s) (BCR) for storage, quality control, processing into molecular analytes, and other research efforts. Ultimately, the samples will be characterized for copy number variation, single nucleotide polymorphisms, epigenomic profiles, gene and miRNA expression and mutation analysis.
 
Project Terms:
atlases biobank blood cancer diagnosis cancer genome cell nucleus clinical data clinical research site collection consent contractor copy number polymorphism diagnosis dna ensure epigenomics excision follow-up freezing genes institution malignant neoplasms micrornas molecular mutation analysis necrosis patients process programs prospective protocols documentation qualifying quality control recovery research resources sampling series shipping ships single nucleotide polymorphism site source time tissues tumor cancer genetic testing genetics human genome
Project Title: Arra::yes::arra tas::75 0850::tas recovery act - sequencing for the cancer genom
Project Number: 261201000055C-2-0-1
Project web address: Follow on NIH
Organization: Broad Institute, Inc., United States, Massachusetts, CAMBRIDGE
Principal Investigators (PI): Gabriel Stacey, US
 
Project Categories:
Natural Sciences > Aging Diseases and Pathology > Cancer & related diseases > Malignant neoplasms (including in situ)
 
Other Information:
Fiscal Year: 2010
Project Start Date: 24 September 2010
Project End Date: 23 March 2012
 
Project Funding Information:
Funding Mechanism: Contracts, Extramural
Year Funding Organization Total Funding, $
2010 NIH - National Cancer Institute $30,965,067
Project Title: Arra::yes::arra tas::75 0850::tas recovery act - sequencing for the cancer genom
Project Number: 261201000055C-2-0-1
Project web address: Follow on NIH
Organization: Broad Institute, Inc., United States, Massachusetts, CAMBRIDGE
Principal Investigators (PI): Gabriel Stacey, US
 
Title FY Funding
There are no results for this project in database.
Project Title: Arra::yes::arra tas::75 0850::tas recovery act - sequencing for the cancer genom
Project Number: 261201000055C-2-0-1
Project web address: Follow on NIH
Organization: Broad Institute, Inc., United States, Massachusetts, CAMBRIDGE
Principal Investigators (PI): Gabriel Stacey, US
 
Project Title Organization FY Funding
Arra::Yes::Arra Tas::75 0850::Tas Recovery Act - Sequencing For The Cancer GenomBroad Institute, Inc.2010$30,965,067
Project Title: Arra::yes::arra tas::75 0850::tas recovery act - sequencing for the cancer genom
Project Number: 261201000055C-2-0-1
Project web address: Follow on NIH
Organization: Broad Institute, Inc., United States, Massachusetts, CAMBRIDGE
Principal Investigators (PI): Gabriel Stacey, US
 
Project number Project title Principal investigator
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Project Title: Arra::yes::arra tas::75 0850::tas recovery act - sequencing for the cancer genom
Project Number: 261201000055C-2-0-1
Project web address: Follow on NIH
Organization: Broad Institute, Inc., United States, Massachusetts, CAMBRIDGE
Principal Investigators (PI): Gabriel Stacey, US
 
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