Laboratory support services

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Project Title: Laboratory support services
Project Number: 1ZIDAI009004-08
Project web address: Follow on NIH
Organization: Niaid Extramural Activities, United States
Principal Investigators (PI): Siddiqui Sophia, US
 
Project Description:
The NIAID Division of Clinical Research (DCR) provides effective rapid response to urgent and compelling public health concerns through program-dedicated research support to NIAID activities. DCR, via a contract mechanism with Leidos Biomedical Research, Inc. provides Laboratory Support Services through state-of-art facilities to support NIAID clinical studies. These services establish immunologic profiles of patient specimens in support of the NAID intramural program commitment to AIDS clinical research, and to study of neutrophils from chronic granulomatous disease (CGD) patients. Also this contract establishes techniques for studying antigen and antibody response to various influenza in both natural history and treatment protocols. Procedures to be performed include, but not limited to: (i) enumeration of lymphocyte subsets; (ii) cell sorting; (iii) proliferative responses of lymphocytes to mitogens and antigens; (iv) serum/plasma biomarkers; (v) viral loads for HIV and HCV; (vi) HIV genotyping; (vii) deep sequencing, (viii) cytokine assays. When appropriate, testing procedures are to be performed under auspices of Clinical Laboratory Improvement Amendments CLIA. DCR maintains rigorous quality assurance and quality control standards, organizes and helps analyze data generated from its studies, and helps prepare these data for presentation and publication. During FY16, the NIAID DCR Laboratory Support Services provided lab services to support the conduct of approximately 75 clinical trials for Laboratory of Immunoregulation (LIR), Laboratory of Host Defenses (LHD) and Laboratory of Clinical Infectious Diseases (LCID).
 
Project Terms:
acquired immunodeficiency syndrome amendment antibody response antigens arts bench to bedside biological assay biological markers biomedical research cell separation chronic granulomatous disease clinical clinical research clinical trials communicable diseases contracts cytokine data data analyses deep sequencing genotype hiv hiv/hcv host defense immunologic monitoring immunologics immunoregulation influenza intramural research program laboratories lymphocyte lymphocyte subset mitogens monitor national institute of allergy and infectious disease natural history neutrophil patients plasma procedures profiles in patients programs public health publications quality assurance quality control research support response services specimen techniques testing translational medicine treatment protocols viral load result biodefense clinical trials and supportive activities emerging infectious diseases hiv/aids infectious diseases
Project Title: Laboratory support services
Project Number: 1ZIDAI009004-08
Project web address: Follow on NIH
Organization: Niaid Extramural Activities, United States
Principal Investigators (PI): Siddiqui Sophia, US
 
Project Categories:
Natural Sciences > Aging Diseases and Pathology > Immune system disorders and inflammation > Aging of immune cells (including HIV effects)
 
Other Information:
Fiscal Year: 2016
Project Start Date: 1 January 2015
Project End Date: 31 December 2016
 
Project Funding Information:
Funding Mechanism: Intramural Research
Year Funding Organization Total Funding, $
2016 NIH - National Institute Of Allergy And Infectious Diseases $23,013,194
Project Title: Laboratory support services
Project Number: 1ZIDAI009004-08
Project web address: Follow on NIH
Organization: Niaid Extramural Activities, United States
Principal Investigators (PI): Siddiqui Sophia, US
 
Title FY Funding
There are no results for this project in database.
Project Title: Laboratory support services
Project Number: 1ZIDAI009004-08
Project web address: Follow on NIH
Organization: Niaid Extramural Activities, United States
Principal Investigators (PI): Siddiqui Sophia, US
 
Project Title Organization FY Funding
Laboratory Support ServicesNiaid Extramural Activities2016$23,013,194
Project Title: Laboratory support services
Project Number: 1ZIDAI009004-08
Project web address: Follow on NIH
Organization: Niaid Extramural Activities, United States
Principal Investigators (PI): Siddiqui Sophia, US
 
Project number Project title Principal investigator
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Project Title: Laboratory support services
Project Number: 1ZIDAI009004-08
Project web address: Follow on NIH
Organization: Niaid Extramural Activities, United States
Principal Investigators (PI): Siddiqui Sophia, US
 
Title Journal Year Country Rel
The effects of storage temperature on PBMC gene expression. BMC Immunol 2016 england