Inner city asthma consortium 3 (icac3)

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Project Title: Inner city asthma consortium 3 (icac3)
Project Number: 1UM1AI114271-01
Project web address: Follow on NIH
Organization: University Of Wisconsin-Madison, United States, Wisconsin, MADISON
Principal Investigators (PI): Busse William, US
Gern James E, US
 
Project Description:
ICAC's goal is to include further development of cockroach allergen immunotherapy and consideration of new allergen immunotherapies; for example to mouse allergens; the development and execution of clinical and mechanistic studies targeted to inner-city asthma phenotypes, and interventions designed to prevent the incidence of asthma or its progression. In addition, the URECA birth cohort study will be continued to the end of the grant, when the participants will range from 14 to 16 years of age, with the goal to provide information on the immunologic basis of late childhood and adolescence-onset asthma, as well as the remission of asthma during the same years.
 
Project Terms:
16 year old address adolescence adolescent airborne allergen allergen immunotherapy allergens allergic allergic airway disease anti-cholinergics asthma bacteria base biological birth caring cells characteristics child childhood childhood asthma clinical cockroach allergen cohort cohort studies collaborations complex design development dictyoptera disease disease progression disease remission disorder control early childhood environment environmental exposure environmental risk factor epidemic epigenetic process epitopes exposure to gastrointestinal genetic risk factor goals grant guidelines high risk house dust household ige immune immune response immunobiology immunologics immunoregulation immunotherapy improved in utero incidence infancy inner city interleukin-5 intervention lead leptin life link mediating mepolizumab metabolic microbe microbial microbiome mus muscarinic antagonists obesity omalizumab outcome participant patients peripheral blood eosinophilia phenotype plasma population prevalence prevent prevention process protocols documentation recurrence research design respiratory respiratory tract infections response risk risk factors role school-age population severities shapes source stimulus subcutaneous systems biology t cell response t-lymphocyte testing therapy design wheezing work clinical research lung pediatric pediatric research initiative
Project Title: Inner city asthma consortium 3 (icac3)
Project Number: 1UM1AI114271-01
Project web address: Follow on NIH
Organization: University Of Wisconsin-Madison, United States, Wisconsin, MADISON
Principal Investigators (PI): Busse William, US
Gern James E, US
 
Project Categories:
Natural Sciences > Aging Diseases and Pathology
 
Other Information:
Fiscal Year: 2014
Project Start Date: 5 August 2014
Project End Date: 31 July 2021
Project program: Research Project with Complex Structure Cooperative Agreement
 
Project Funding Information:
Funding Mechanism: Non-SBIR/STTR RPGs
Year Funding Organization Total Funding, $
2014 NIH - National Institute Of Allergy And Infectious Diseases $9,949,825
Project Title: Inner city asthma consortium 3 (icac3)
Project Number: 1UM1AI114271-01
Project web address: Follow on NIH
Organization: University Of Wisconsin-Madison, United States, Wisconsin, MADISON
Principal Investigators (PI): Busse William, US
Gern James E, US
 
Title FY Funding
There are no results for this project in database.
Project Title: Inner city asthma consortium 3 (icac3)
Project Number: 1UM1AI114271-01
Project web address: Follow on NIH
Organization: University Of Wisconsin-Madison, United States, Wisconsin, MADISON
Principal Investigators (PI): Busse William, US
Gern James E, US
 
Project Title Organization FY Funding
Inner City Asthma Consortium 3 (Icac3)University Of Wisconsin-Madison2016$10,328,678
Inner City Asthma Consortium 3 (Icac3)University Of Wisconsin-Madison2015$12,125,381
Inner City Asthma Consortium 3 (Icac3)University Of Wisconsin-Madison2014$9,949,825
Project Title: Inner city asthma consortium 3 (icac3)
Project Number: 1UM1AI114271-01
Project web address: Follow on NIH
Organization: University Of Wisconsin-Madison, United States, Wisconsin, MADISON
Principal Investigators (PI): Busse William, US
Gern James E, US
 
Project number Project title Principal investigator
There are no any related projects.
Project Title: Inner city asthma consortium 3 (icac3)
Project Number: 1UM1AI114271-01
Project web address: Follow on NIH
Organization: University Of Wisconsin-Madison, United States, Wisconsin, MADISON
Principal Investigators (PI): Busse William, US
Gern James E, US
 
Title Journal Year Country Rel
Asthma phenotypes in inner-city children. J Allergy Clin Immunol 2016 united states
The influence of atopy and asthma on immune responses in inner-city adults. Immun Inflamm Dis 2016 england
Rhinoviruses and Their Receptors: Implications for Allergic Disease. Curr Allergy Asthma Rep 2016 united states
Reducing Exacerbations in the Inner City: Lessons from the Inner-City Asthma Consortium (ICAC). J Allergy Clin Immunol Pract 2016 united states
Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells. Virology 2016 united states
The contributions of allergic sensitization and respiratory pathogens to asthma inception. J Allergy Clin Immunol 2016 united states
Effects of omalizumab on T lymphocyte function in inner-city children with asthma. Pediatr Allergy Immunol 2016 england
The microbiome and development of allergic disease. Curr Opin Allergy Clin Immunol 2016 united states
Influence of early-life exposures on food sensitization and food allergy in an inner-city birth cohort. J Allergy Clin Immunol 2015 united states
Promising candidates for allergy prevention. J Allergy Clin Immunol 2015 united states
Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes. J Immunol Methods 2015 netherlands
Microbiota in allergy and asthma and the emerging relationship with the gut microbiome. Cell Host Microbe 2015 united states
Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol 2014 united states